Anastasia Anime
Anime rankingsTop Isekai anime of 2022
A new world does not always mean a fresh start comes easily. Discover the top isekai anime of 2022, where unfamiliar rules, unexpected powers, and dangerous encounters turn an ordinary life into an extraordinary journey. Choose the world you want to explore next.
#10Arifureta Shokugyou de Sekai Saikyou: Maboroshi no Bouken to Kiseki no Kaigou
From a Commonplace Job to the World's Strongest: Phantom Adventure and Miraculous Encounter
Back from the Sunken Ruins of Melusine, Hajime knows that his coming farewell with Myu is close, so he decides to give her one last adventure before the journey continues. The group talks about the Seven Great Legends of Erisen and tries following them, but the first stories lead nowhere. The seventh, however, brings them face to face with a giant creature that throws them into a mysterious ruined city.Myu becomes separated from the group, and Hajime's search for her leads to an impossible encounter: the legendary Liberators are trapped in the same place, having arrived from another era. To return everyone to their proper time, the two groups must fight together in an adventure that briefly brings past and present into the same world.
#9Akuyaku Reijou nanode Last Boss wo Kattemimashita
I'm a Villainess, So I Tried Taming the Final Boss
Aileen Lauren Dautriche's engagement to Crown Prince Cedric is publicly broken, and in the middle of the humiliation memories from her previous life return. She realizes she has been reincarnated inside an otome game as its villainess, complete with knowledge of the ending waiting for her: within months, she is destined to die at the hands of Claude, Cedric's half-brother and the story's “final boss,” the Demon King. Instead of waiting, Aileen decides to break the script and asks the most dangerous man in it to marry her. Claude distrusts her, so she begins proving herself by helping protect demonic beasts and pursue peace with humans. The further she moves away from the original story, the more she discovers that the game contained more than one bad ending.
#8Isekai Yakkyoku
Pharmacy in Another World
Pharmacological researcher Kanji Yakutani devoted his life to medicine after losing his younger sister to an illness treatment could not save, only to die himself from overwork. He awakens in another world as Falma de Medicis, a child from a prestigious family of royal pharmacists, carrying both his previous medical knowledge and a divine ability that lets him understand and create substances. Falma quickly discovers that medicine here relies on outdated beliefs and that effective care is treated as a privilege of the wealthy. Refusing to accept that system, he applies modern science and careful diagnosis to open a pharmacy for ordinary people, challenging monopolies, superstition, and the social limits placed on who deserves treatment.
#7Otome Game Sekai wa Mob ni Kibishii Sekai desu
The World of Otome Games Is Harsh on Background Characters
After finishing an absurdly difficult romance game, an office worker dies and is reborn inside its world as Leon Fou Bartfort, a minor noble who was never supposed to matter. Leon wants a quiet life, but this society favors women and handsome high-ranking men while treating someone like him as disposable. His knowledge of the game helps him recover a lost AI and technology that gives far too much power to a person trying to stay in the background. When another reincarnated player disrupts the original route and harms Olivia and Angelica, Leon cannot ignore it. He enters duels against spoiled princes and keeps winning, only to discover that every victory creates a new problem by raising his status and dragging him further from the anonymous life he wanted.
#6Isekai Quartet Movie: Another World
Isekai Quartet: Another World
A wormhole suddenly opens in the classroom and drags the already mismatched students into yet another world. Ainz, Tanya, Kazuma, Subaru, and the rest of the class land in a desolate place dominated by giant magical automata that have run out of control, with no obvious route home. Their search leads them to a girl-shaped golem whose behavior feels strangely familiar, a woman wearing a military uniform much like Tanya's, and a man with a cane who seems to know Subaru. Surrounded by mysteries and their usual misunderstandings, the class has to cooperate once again if they want to escape this new world.
#5Tensei shitara Ken deshita
When I Reincarnated, I Was a Sword
A man dies and awakens in another world not as a warrior or mage, but as a sentient sword. Able to move with telekinesis and absorb skills from the monsters he defeats, he spends his new life growing stronger until an accident leaves him stuck and unable to continue alone. His wielder finally arrives in the form of Fran, a young Black Cat beastkin escaping slavery. With the sword's power, she wins her freedom and names him Shishou, or Teacher. The two become an unconventional master-and-student pair of adventurers, pursuing greater strength for a deeply personal reason: Fran wants to achieve the evolution no member of her tribe has ever reached.
#4Tensei shitara Slime Datta Ken Movie: Guren no Kizuna-hen
That Time I Got Reincarnated as a Slime: The Movie - Scarlet Bond
West of Tempest lies the small kingdom of Raja, a land whose survival depends on the mysterious power of its queen. When Rimuru Tempest and his companions become involved in a crisis there, Benimaru encounters someone he never expected to see: Hiiro, another survivor of the ogre village destroyed years earlier and a man he once regarded as an older brother. Hiiro now serves Raja and is willing to risk everything for its queen, but the power sustaining the country is tied to a conspiracy that has been unfolding for years. Rimuru wants to help without turning Raja into another battlefield, while Benimaru must confront a bond from before Tempest existed and decide how to save someone who may already be trapped by his loyalty.
#3Isekai Ojisan
Uncle from Another World
Takafumi's uncle wakes after seventeen years in a coma and calmly claims he spent that entire time in a magical world. Takafumi assumes his mind has not recovered until the man demonstrates real magic. His uncle truly returned with supernatural powers and memories full of monsters and adventure, but he also missed nearly two decades of technology, culture, and especially video-game history that matters to him far more than it probably should. The two use magic to make online videos and earn money while the uncle replays his old adventures like living recordings. The most astonishing part of those memories is often not the monsters, but the obvious romantic signals he somehow failed to understand.
#2Overlord IV
Overlord IV
Ainz Ooal Gown now rules the Sorcerer Kingdom, but an undead monarch inspires fear far faster than trust. Trade slows and neighboring nations watch him carefully, while Ainz hopes to build a realm where different races can live and prosper together. The problem is that his followers treat every casual remark as part of a brilliant plan for world domination and carry out what they think he meant with terrifying devotion. Empires, alliances, and religious powers maneuver around him, drawing his growing kingdom toward dwarven lands and eventually a major confrontation with Re-Estize. Through misunderstanding and ambition, the surrounding nations learn that resisting Ainz may be far more dangerous than trying to understand him.
#1Kage no Jitsuryokusha ni Naritakute!
I Want to Become a Power in the Shadows!
Since childhood, Cid Kagenou has never wanted to be the famous hero. He wants to be the mysterious power operating from the shadows, appearing only at the perfect moment. Reborn in a world of magic, he finally has the setting to build that identity for real. He creates Shadow Garden and invents a story about a secret Cult of Diablos simply to make the role more convincing. The problem is that the cult actually exists. His followers uncover genuine conspiracies and atrocities while Cid assumes they are merely playing along. He enters a very real war convinced he is performing the greatest role of his life, unaware that the world has taken his fantasy completely seriously.
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